NDM-1 is an enzyme that makes bacteria resistant to a broad range of beta-lactam antibiotics. NDM-1 was first identified in December 2009 in a patient hospitalized in New Delhi with an infection caused by Klebsiella pneumoniae. It was later detected in bacteria in India, Pakistan, the United Kingdom, the United States, and Canada.
MMWR - June 25, 2010
Detection of Enterobacteriaceae Isolates Carrying Metallo-Beta-Lactamase --- United States, 2010.
Emergence of a new antibiotic resistance mechanism - Volume 10, Issue 9, Pages 597 - 602, September 2010
The Lancet Infectious Diseases Journal acticle.
MMWR - March 20, 2009
Guidance for Control of Infections with Carbapenem-Resistant or Carbapenemase-Producing Enterobacteriaceae in Acute Care Facilities.
CIDRAP - Aug 20, 2010
Experts offer perspective on NDM-1 resistance threat.