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Medical and Research Library News - October 2017

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News and training opportunities
Cool websites and reports on hot topics
Interesting journal articles
New Books

October 2017

mrl-diamondNews and training opportunities

FREE continuing education from Medscape and MMWR: Update on U.S. pregnant women and infants with recent Zika virus exposure. Because the full clinical spectrum of congenital Zika virus infection is not yet known, all infants born to women with laboratory evidence of possible recent Zika virus infection during pregnancy should receive postnatal neuroimaging and Zika virus testing in addition to a comprehensive newborn physical exam and hearing screen. (To get CME credit, you will need to register with Medscape. Registration is free.) See https://www.cdc.gov/mmwr/cme/medscape_cme.html 

October 3, 2017; Noon – 1 p.m. Viral Information and Digital Pandemics: When Public Health and the World Wide Web Collide, presented by Brittany Seymour, DDS, MPH. Her research explores online health information (and misinformation) in the context of media communication theory and network science. See https://rohdeo.uthscsa.edu/webinars.php 

October 5, 2017; 1 - 2 p.m. Workplace Wellness: Walk This Way. Attendees will learn to identify potential state and local policies that support physical activity and wellness in the workplace and beyond, to describe the relationship between workplace wellness and active transportation, and understand how to use a new Walk This Way resource to support wellness and physical activity. See http://americawalks.org/new-webinar-workplace-wellness-walk-this-way-october-5-2017/ 

October 12, 2017; 1 – 2:15 p.m. Stepping Up: Tracking Progress on Reducing the Number of People with Mental Illnesses in Jails. This webinar will discuss how to track progress on the four key measures for reducing the number of people with mental illnesses in jail (the number of people with mental illnesses booked into jail, their length of stay in jail, connections to treatment and recidivism). See https://register.gotowebinar.com/register/1181365155627140354 

October 12, 2017; 1 - 2:30 p.m. Niños saludables: Addressing Childhood Obesity among Latinos. This webinar sponsored by the federal Office of Minority Health will highlight the prevalence data and explore factors such as culture, behavior, and environment; that have contributed to the increase of obesity in Latino children of all ages over the past 30 years. See https://register.gotowebinar.com/register/666768424642843650

October 18, 2017; 10 – 11 a.m. Support for Healthy Breastfeeding Mothers with Healthy Term Babies: What’s the evidence? Health Evidence will be hosting a webinar examining breastfeeding support interventions for healthy breastfeeding mothers with healthy term babies. See https://health-evidence.webex.com/mw3200/mywebex/default.do?nomenu=true&siteurl=health-evidence&service=6&rnd=0.4435671950452098&main_url=https%3A%2F%2Fhealth-evidence.webex.com%2Fec3200%2Feventcenter%2Fevent%2FeventAction.do%3FtheAction%3Ddetail%26%26%26EMK%3D4832534b0000000456206200d015ae30d2e689c5075a84c1e017efbfb6f22949d130e3d1113984a2%26siteurl%3Dhealth-evidence%26confViewID%3D67835097475219450%26encryptTicket%3DSDJTSwAAAAThwcSXjYuuPe-wETvQMwJ6BCXT09St1rBzwTd46fSlFA2%26

October 18, 2017; 11 – Noon. Financing and Service Delivery Integration for Mental Illness & Substance Abuse.  Building on integrated data sources from Arizona’s medical, mental health, and criminal justice systems, this project explores opportunities to better coordinate services for persons with mental illness and/or substance abuse disorders. Using interactive system dynamics modeling and network analysis methods, pathways are mapped for people and dollars moving between and within the state’s medical, mental health, and criminal justice systems. See https://cc.readytalk.com/registration/#/?meeting=fedgipcdfdlc&campaign=310e36wlumho

October 23, 2017; 12:30 – 1:30 p.m. A Model Population Health Initiative: Reducing Costs by Going Upstream. This webinar will highlight the winner of the 2017 Future of Population Health Award, telling the story of a medical center that chose to address an upstream cause of repeat hospitalizations for chronic diseases among the homeless. The program has significantly reduced use of hospital services and costs. See https://register.gotowebinar.com/register/2021523980086692353 

mrl-diamondCool websites and reports on hot topics

10 Policies to Prevent and Respond to Childhood Lead Exposure, Health Impact Project, 2017. This is an assessment of the risks communities face and key federal, state, and local solutions related to childhood lead exposure. It performs a cost-benefit analysis of various policies to prevent and respond to the problem. See http://www.pewtrusts.org/~/media/assets/2017/08/hip_childhood_lead_poisoning_report.pdf

A Comprehensive Plan for State-Funded Inpatient Mental Health Services as required by Texas S.B. 1, 85th Legislature, Health and Human Services, August 2017. This plan outlines the agency’s vision for the state hospital system and other state-funded inpatient mental health care over the coming biennia. See https://hhs.texas.gov/sites/default/files/documents/about-hhs/process-improvement/comprehensive-inpatient-mental-health-plan-8-23-17.pdf

Cost of Community Violence to Hospitals and Health Systems, Report for the American Hospital Association, July 26, 2017. This report estimates that proactive and reactive violence response efforts cost U.S. hospitals and health systems approximately $2.7 billion in 2016, including $280 million related to preparedness and prevention to address community violence, $852 million in unreimbursed medical care for victims of violence, $1.1 billion in security and training costs to prevent violence within hospitals, and $429 million in medical care, staffing, indemnity, and other costs as a result of violence against hospital employees. See http://www.aha.org/content/17/community-violence-report.pdf 

Foodsafety.gov: This web portal provides information on food recalls, how to keep food safe, food poisoning, vulnerable populations, and how to report issues with food items. Right now information on food safety tips for emergencies is featured. See https://www.foodsafety.gov/index.html

Hurricane Harvey: Recover from Hurricane Harvey. This is a compilation of all types of federal response information for victims of Hurricane Harvey. See https://www.usa.gov/hurricane-harvey

Hurricanes of 2017: Information from the Disaster Information Management Research Center on health-related topics for all of the 2017 hurricanes is located on this one page. See https://disasterinfo.nlm.nih.gov/dimrc/hurricanesof2017.html#a2

Key Substance Use and Mental Health Indicators in the United States: Results from the 2016 National Survey on Drug Use and Health. This report from SAMHSA presents 2016 national estimates of use of alcohol, tobacco products, illicit drugs, substance use disorders, and substance use treatment among people 12 years of age and older. It also includes national estimates of any mental illness. See https://store.samhsa.gov/shin/content/SMA17-5044/SMA17-5044.pdf 

Preventing Cognitive Decline and Dementia: A Way Forward (2017) by the National Academies of Sciences, Engineering, and Medicine. This report assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. See https://www.ncbi.nlm.nih.gov/books/NBK436397/pdf/Bookshelf_NBK436397.pdf

Public Health 3.0: A Call to Action for Public Health to Meet the Challenges of the 21st Century. Prev Chronic Dis 2017;14:170017. Stressors on public health are driving many local governments to pioneer a new Public Health 3.0 model in which leaders serve as Chief Health Strategists, partnering across multiple sectors and leveraging data and resources to address social, environmental, and economic conditions that affect health and health equity. See http://nam.edu/public-health-3-0-call-action-public-health-meet-challenges-21st-century/

State Approaches to Reducing Health Disparities, National Conference of State Legislatures, June 2017. This brief explores health disparities with a focus on differences across racial and ethnic groups, recent state action to address disparities, and policy options for legislators to consider in their states. See http://www.ncsl.org/Portals/1/Documents/Health/HealthDisparities_2017_31448.pdf

Young Adults and Transitioning Youth with Autism Spectrum Disorder, Report to Congress Submitted by the National Autism Coordinator of the U.S. Department of Health and Human Services, August 3, 2017. The purposes of this report are to summarize existing federal investments focused on the transition period from childhood to adulthood for individuals with ASD and to identify gaps in federal research, programs, and services that support youth with ASD during this critical time period. See https://www.hhs.gov/sites/default/files/2017AutismReport.pdf

mrl-diamondInteresting journal articles

Adverse health complaints of adults exposed to benzene after a flaring disaster at the BP refinery facility in Texas City, Texas. D'Andrea MA, Reddy GK. Disaster Med Public Health Prep. 2017 Sep 7:1-9. doi: 10.1017/dmp.2017.59. [Epub ahead of print]
Objective: The objective of this study was to assess the adverse health symptoms experienced by adult subjects who were exposed to benzene after a flaring disaster at the BP refinery in Texas City, Texas. Methods: A total of 2162 adults aged 18 years or older and exposed to benzene were included. Using the patients' medical charts, we collected and analyzed data on health complaints as well as the patients' serum levels of beta-2-microglobulin and urinary excretion of phenol. Results: A total of 11,368 health symptom complaints were reported in 2162 adults exposed to benzene. Neurological symptoms occurred most frequently (174%), followed upper respiratory symptoms (115%), cough (31%), painful joints (30%), cardiac symptoms (28%), dermatological symptoms (28%), gastrointestinal symptoms (27%), diarrhea (25%), vision symptoms (21%), and nausea/vomiting (19%). Logistic regression analysis indicated that urinary symptoms (R2=0.65) and painful joints (R2=0.44) were positively associated with increasing age in benzene-exposed subjects. Conclusion: Adult subjects exposed to benzene experience a range of adverse health symptoms and an altered profile of urinary phenol, thus indicating they are at high risk of developing serious future health complications.

The association between dental, general, and mental health status among underserved and vulnerable populations served at health centers in the US. Nguyen VH, Lin SC, Cappelli DP, Nair S. J Public Health Dent. 2017 Jul 18. doi: 10.1111/jphd.12234. [Epub ahead of print]
Objectives: Vulnerable populations in underserved communities are disproportionately at high risk for multiple medical, dental, and behavioral health conditions. This study aims to: a) examine the occurrence of acute dental needs and b) investigate the association of acute dental needs and self-rated general and mental health status among the adult dentate health center population. Methods: This cross-sectional study analyzed data on adult patients (n = 5,035) from the 2014 Health Center Patient Survey, a nationally representative survey of health center patients. Multivariate logistic regression was used to assess the association of acute dental needs and a) self-rated general health status and b) mental health status. Results: Approximately, two thirds of adult dentate heath center patients reported having an acute dental need. After adjusting for confounding factors, not having or having had health insurance that pays for dental care, general health status of fair or poor, and ever having a mental illness were associated with higher odds of having an acute dental need. Conclusions: The results highlight the role of health centers in addressing oral health disparities among vulnerable populations and the importance of a team-based multidisciplinary approach to ensuring the integration and coordination of oral health services within a comprehensive primary care delivery system.

CDC Grand Rounds: Newborn screening for hearing loss and critical congenital heart disease. Grosse SD, Riehle-Colarusso T, Gaffney M, et al. MMWR Morb Mortal Wkly Rep. 2017 Aug 25;66(33):888-890.
Newborn screening is a public health program that benefits 4 million U.S. infants every year by enabling early detection of serious conditions, thus affording the opportunity for timely intervention to optimize outcomes (1). States and other U.S. jurisdictions decide whether and how to regulate newborn screening practices. Most newborn screening is done through laboratory analyses of dried bloodspot specimens collected from newborns. Point-of-care newborn screening is typically performed before discharge from the birthing facility. The Recommended Uniform Screening Panel includes two point-of-care conditions for newborn screening: hearing loss and critical congenital heart disease (CCHD). The objectives of point-of-care screening for these two conditions are early identification and intervention to improve neurodevelopment, most notably language and related skills among infants with permanent hearing loss, and to prevent death or severe disability resulting from delayed diagnosis of CCHD. Universal screening for hearing loss using otoacoustic emissions or automated auditory brainstem response was endorsed by the Joint Committee on Infant Hearing in 2000 and 2007* and was incorporated in the first Recommended Uniform Screening Panel in 2005. Screening for CCHD using pulse oximetry was recommended by the Advisory Committee on Heritable Disorders in Newborns and Children in 2010 based on an evidence review† and was added to the Recommended Uniform Screening Panel in 2011.§.

Common and critical components among community health assessment and community health improvement planning models. Pennel CL, Burdine JN, Prochaska JD, McLeroy KR. J Public Health Manag Pract. 2017 Jul/Aug;23 Suppl 4 Supplement, Community Health Status Assessment:S14-S21.
Community health assessment and community health improvement planning are continuous, systematic processes for assessing and addressing health needs in a community. Since there are different models to guide assessment and planning, as well as a variety of organizations and agencies that carry out these activities, there may be confusion in choosing among approaches. By examining the various components of the different assessment and planning models, we are able to identify areas for coordination, ways to maximize collaboration, and strategies to further improve community health. We identified 11 common assessment and planning components across 18 models and requirements, with a particular focus on health department, health system, and hospital models and requirements. These common components included preplanning; developing partnerships; developing vision and scope; collecting, analyzing, and interpreting data; identifying community assets; identifying priorities; developing and implementing an intervention plan; developing and implementing an evaluation plan; communicating and receiving feedback on the assessment findings and/or the plan; planning for sustainability; and celebrating success. Within several of these components, we discuss characteristics that are critical to improving community health. Practice implications include better understanding of different models and requirements by health departments, hospitals, and others involved in assessment and planning to improve cross-sector collaboration, collective impact, and community health. In addition, federal and state policy and accreditation requirements may be revised or implemented to better facilitate assessment and planning collaboration between health departments, hospitals, and others for the purpose of improving community health.

Examining mosquito surveillance and control capacity in the top 10 areas at risk for Zika virus exposure in the United States. Gridley-Smith CL. J Public Health Manag Pract. 2017 Sep/Oct;23(5):515-517.
NACCHO assessed mosquito surveillance and control activities across 10 high-risk jurisdictions (Alabama, Arizona, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, Texas, and Los Angeles County), each identified as potentially vulnerable to Zika infection.

Happiness traps: how we sabotage ourselves at work. McKee A. Harvard Business Review. 2017 Sep/Oct;95(5):66-73.
Numerous studies show that close to two-thirds of U.S. employees are bored, detached, or jaded and ready to sabotage plans, projects, and other people. Why so much unhappiness among professionals who have the capacity to shape their work lives? The author highlights three of the most common reasons—ambition, doing what’s expected of us, and overwork—which seem productive on the surface but are harmful when taken to the extreme. To break free of these “happiness traps,” you first have to accept that you deserve happiness at work. Then you can use your emotional intelligence—particularly emotional self-awareness, emotional self-control, and organizational awareness— to understand which trap has ensnared you. Finally, you must actively seek meaning and purpose in day-to-day activities, foster hope in yourself and others, and build friendships at work.

Hookah use among adolescents: differential cognitions about hookah and cigarettes. Barnett TE, Livingston MD. Addict Behav. 2017 Dec;75:75-78.
Background: Hookah use is prevalent among adolescent and young adult populations. The study assessed how positive cognitions toward cigarettes moderate the impact of positive hookah cognitions on past 30-day hookah use among a representative sample of youth. Understanding cognitions about products can contribute to effective interventions. Methods: Data from the 2015 Florida Youth Tobacco Survey was used to determine cognitions and use patterns among high school students. Weighted means and proportions were used for demographic comparisons for cognitions about products. t-Tests and chi-square analysis were conducted for differences between users and non-users. Logistic regressions were conducted for the modeling of interaction between hookah and cigarette cognition. Results: Nearly one out of ten (9.6%) of adolescents reported current hookah use. Across all cognition measures, positive hookah cognitions were associated with current hookah use. Additionally, there was a pattern of hookah cognitions being more strongly associated with current hookah use among those students that did not endorse the equivalent cognition for traditional cigarettes. Conclusions: Hookah cognitions were generally more associated with hookah use among youth who did not endorse positive cognitions for cigarettes compared to those that did endorse positive cognitions for cigarettes. This finding is novel given youth who feel negatively about cigarettes are more influenced by their hookah-specific cognitions. Youth who believe cigarettes pose harm may benefit from messaging about the harms of hookah. Interventions or prevention efforts that draw strong comparisons between cigarettes and hookah may be effective among youth.

Opioid drug use and acute cardiac events among pregnant women in the United States. Salihu HM, Salemi JL, Aggarwal A, et al. Am J Med. 2017 Aug 11. pii: S0002-9343(17)30806-9. doi: 10.1016/j.amjmed.2017.07.023. [Epub ahead of print]
Background: Cardiovascular disease remains a leading cause of pregnancy-associated deaths in the United States (US). The extent to which increasing opioid use among pregnant women contributes to fatal cardiovascular events is unknown. We examine trends in opioid use among pregnant women over the previous decade, and the association between changes in temporal trends in opioid drug use and the incidence of acute cardiac events among mothers. Methods: In this retrospective analysis of the Healthcare and Cost Utilization Project (HCUP), we utilized a two-stage stratified cluster sampling of all inpatient hospital discharges from non-federal hospitals between 01/01/2002 through 12/31/2014. The study population comprised pregnant women aged 13-49 years and related hospitalizations, including delivery. The primary exposure of interest was opioid use during pregnancy. The primary outcome was the occurrence of acute myocardial infarction or cardiac arrest during pregnancy or childbirth. Results: Among the estimated 57.4 million pregnancy-related inpatient hospitalizations, 511,469 (approximately 1%) had documented use of opioids, cocaine, and/or amphetamines. There was a 300% increase in the use of opioids during pregnancy over the study period, while cocaine consumption significantly decreased and that of amphetamine remained stable. Over the 13-year period, the rise in opioid use paralleled a 50% increase in the incidence of acute cardiac events among mothers. Conclusion: Over the previous decade, opioid use during pregnancy increased significantly, in parallel with the rise in the incidence of acute cardiac events in pregnancy and childbirth. An effective national policy is needed to address this emerging public health challenge.

Patterns of sedentary behavior and mortality in U.S. middle-aged and older adults: a national cohort study. Diaz KM, Howard VJ, Hutto B, et al. Ann Intern Med. 2017 Sep 12. doi: 10.7326/M17-0212. [Epub ahead of print]
Background: Excessive sedentary time is ubiquitous in Western societies. Previous studies have relied on self-reporting to evaluate the total volume of sedentary time as a prognostic risk factor for mortality and have not examined whether the manner in which sedentary time is accrued (in short or long bouts) carries prognostic relevance. Objective: To examine the association between objectively measured sedentary behavior (its total volume and accrual in prolonged, uninterrupted bouts) and all-cause mortality. Design: Prospective cohort study. Setting: Contiguous United States. Participants: 7,985 black and white adults aged 45 years or older. Measurements: Sedentary time was measured using a hip-mounted accelerometer. Prolonged, uninterrupted sedentariness was expressed as mean sedentary bout length. Hazard ratios (HRs) were calculated comparing quartiles 2 through 4 to quartile 1 for each exposure (quartile cut points: 689.7, 746.5, and 799.4 min/d for total sedentary time; 7.7, 9.6, and 12.4 min/bout for sedentary bout duration) in models that included moderate to vigorous physical activity. Results: Over a median follow-up of 4.0 years, 340 participants died. In multivariable-adjusted models, greater total sedentary time (HR, 1.22 [95% CI, 0.74 to 2.02]; HR, 1.61 [CI, 0.99 to 2.63]; and HR, 2.63 [CI, 1.60 to 4.30]; P for trend < 0.001) and longer sedentary bout duration (HR, 1.03 [CI, 0.67 to 1.60]; HR, 1.22 [CI, 0.80 to 1.85]; and HR, 1.96 [CI, 1.31 to 2.93]; P for trend < 0.001) were both associated with a higher risk for all-cause mortality. Evaluation of their joint association showed that participants classified as high for both sedentary characteristics (high sedentary time [≥12.5 h/d] and high bout duration [≥10 min/bout]) had the greatest risk for death. Limitation: Participants may not be representative of the general U.S. population. Conclusion: Both the total volume of sedentary time and its accrual in prolonged, uninterrupted bouts are associated with all-cause mortality, suggestive that physical activity guidelines should target reducing and interrupting sedentary time to reduce risk for death.

Public health and economic consequences of vaccine hesitancy for measles in the United States. Lo NC, Hotez PJ. JAMA Pediatr. 2017 Sep 1;171(9):887-892.
Importance: Routine childhood vaccination is declining in some regions of the United States due to vaccine hesitancy, which risks the resurgence of many infectious diseases with public health and economic consequences. There are ongoing policy debates on the state and national level, including legislation around non-medical (personal-belief) exemptions for childhood vaccination and possibly a special government commission on vaccine safety, which may affect vaccine coverage. Objective: To estimate the number of measles cases in US children and the associated economic costs under scenarios of different levels of vaccine hesitancy, using the case example of measles, mumps, and rubella (MMR) vaccination and measles. Design, Setting, And Participants: Publicly available data from the US Centers for Disease Control and Prevention were used to simulate county-level MMR vaccination coverage in children (age 2-11 years) in the United States. A stochastic mathematical model was adapted for infectious disease transmission that estimated a distribution for outbreak size as it relates to vaccine coverage. Economic costs per measles case were obtained from the literature. The predicted effects of increasing the prevalence of vaccine hesitancy as well as the removal of non-medical exemptions were estimated. The model was calibrated to annual measles cases in US children over recent years, and the model prediction was validated using an independent data set from England and Wales. Main Outcomes and Measures: Annual measles cases in the United States and the associated public sector costs. Results: A 5% decline in MMR vaccine coverage in the United States would result in an estimated 3-fold increase in measles cases for children aged 2 to 11 years nationally every year, with an additional $2.1 million in public sector costs. The numbers would be substantially higher if unvaccinated infants, adolescents, and adult populations were also considered. There was variation around these estimates due to the stochastic elements of measles importation and sensitivity of some model inputs, although the trend was robust. Conclusions and Relevance: This analysis predicts that even minor reductions in childhood vaccination, driven by vaccine hesitancy (nonmedical and personal belief exemptions), will have substantial public health and economic consequences. The results support an urgent need to address vaccine hesitancy in policy dialogues at the state and national level, with consideration of removing personal belief exemptions of childhood vaccination.

Tu salud ¡sí cuenta! your health matters! a community-wide campaign in a Hispanic border community in Texas. Heredia NI, Lee M, Mitchell-Bennett L, Reininger BM. J Nutr Educ Behav. 2017 Aug 14. pii: S1499-4046(17)30765-0. doi: 10.1016/j.jneb.2017.06.008. 
Objective: To evaluate a community-wide campaign, Tu Salud ¡Si Cuenta! (TSSC), in improving eating behaviors and anthropometric outcomes in Hispanic border communities. Design: A quasi-experimental study with matched intervention and comparison communities. Cross-sectional assessments with randomly sampled adults, examined by actual exposure and site (unexposed intervention, exposed intervention, and unexposed comparison). Setting and Participants: Predominately Mexican-Americans located in Brownsville, TX (intervention) and Laredo, TX (control). Intervention: The TSSC campaign included television and radio segments, community health worker discussions, and newsletters delivered in Brownsville from 2005 to 2010. Main Outcome Measures: Healthy and unhealthy eating indices and average hip and waist circumferences. Analysis: Univariable and multivariable regression models. Results: The sample (n = 799; 400 comparison and 399 intervention) was 98% of Mexican origin; 54% had completed grade 9 or higher. Exposure to any TSSC component was associated with a lower rate of unhealthy food consumption. Compared with the unexposed intervention group, the exposed intervention for the newsletter had a higher rate of healthy eating (adjusted rate ratio = 1.18; P < .01). Compared with the unexposed intervention, the exposed intervention for the community health worker discussion had a smaller hip circumference (adjusted mean difference = -5.77 cm; P < .05) and a smaller waist circumference (adjusted mean difference = -5.25 cm; P < .05). Conclusions and Implications: This study provides evidence for the use of community-wide campaigns for nutrition and obesity-related outcomes in Hispanic communities.

Using systems science to inform population health strategies in local health departments: a case study in San Antonio, Texas. Li Y, Padron NA, Mangla AT, et al. Public Health Rep. 2017 Jan 1:33354917722149. doi: 10.1177/0033354917722149. 
Objectives: Because of state and federal health care reform, local health departments play an increasingly prominent role leading and coordinating disease prevention programs in the United States. This case study shows how a local health department working in chronic disease prevention and management can use systems science and evidence-based decision making to inform program selection, implementation, and assessment; enhance engagement with local health systems and organizations; and possibly optimize health care delivery and population health. Methods: The authors built a systems-science agent-based simulation model of diabetes progression for the San Antonio Metropolitan Health District, a local health department, to simulate health and cost outcomes for the population of San Antonio for a 20-year period (2015-2034) using 2 scenarios: 1 in which hemoglobin A1c (HbA1c) values for a population were similar to the current distribution of values in San Antonio, and the other with a hypothetical 1-percentage-point reduction in HbA1c values. Results: They projected that a 1-percentage-point reduction in HbA1c would lead to a decrease in the 20-year prevalence of end-stage renal disease from 1.7% to 0.9%, lower extremity amputation from 4.6% to 2.9%, blindness from 15.1% to 10.7%, myocardial infarction from 23.8% to 17.9%, and stroke from 9.8% to 7.2%. They estimated annual direct medical cost savings (in 2015 US dollars) from reducing HbA1c by 1 percentage point ranging from $6842 (myocardial infarction) to $39 800 (end-stage renal disease) for each averted case of diabetes complications. Conclusions: Local health departments could benefit from the use of systems science and evidence-based decision making to estimate public health program effectiveness and costs, calculate return on investment, and develop a business case for adopting programs.

White paper: developing antimicrobial drugs for resistant pathogens, narrow-spectrum indications, and unmet needs. Boucher HW, Ambrose PG, Chambers HF, et al. J Infect Dis. 2017 Jul 15;216(2):228-236.
Despite progress in anti-microbial drug development, a critical need persists for new, feasible pathways to develop antibacterial agents to treat people infected with drug-resistant bacteria. Infections due to resistant gram-negative bacilli continue to cause unacceptable morbidity and mortality rates. Antibacterial agents have been historically studied in non-inferiority clinical trials that focus on a single site of infection (eg, complicated urinary tract infections, intra-abdominal infections), yet these designs may not be optimal, and often are not feasible, for study of infections caused by drug-resistant bacteria. Over the past several years, multiple stakeholders have worked to develop consensus regarding paths forward with a goal of facilitating timely conduct of antimicrobial development. Here we advocate for a novel and pragmatic approach and, toward this end, present feasible trial designs for antibacterial agents that could enable conduct of narrow-spectrum, organism-specific clinical trials and ultimately approval of critically needed new antibacterial agents.

mrl-diamondNew Books

1. 365 Ways to Motivate and Reward Your Employees Every Day-- with Little or No Money, 2nd ed. by Dianna Podmoroff.
2. Agile Project Management: A Quick Start Beginner's Guide to Mastering Agile Project Management, 3rd ed., by Henry O’Brien.
3. The Breast Cancer Survival Manual: A Step-By-Step Guide for Women with Newly Diagnosed Breast Cancer, 5th ed., by John Link et al.
4. Community/Public Health Nursing: Promoting the Health of Populations by Mary A. Nies and Melanie McEwen.
5. A Complaint Is a Gift: Recovering Customer Loyalty When Things Go Wrong by Janelle Barlow and Claus Moller
6. The Enthusiastic Employee: How Companies Profit by Giving Workers What They Want by David Sirota and Douglas A. Klein.
7. Fundamentals of Case Management Practice: Skills for the Human Services by Nancy Summers.
8. Handbook of Stress Coping and Health: Implications for Nursing Research, Theory and Practice, 2nd ed., by Virginia Hill Rice.
9. Landesman's Public Health Management of Disasters: The Practice Guide, 4th ed., by Linda Young Landesman and Rita V. Burke.
10. Learning Tableau 10 by Joshua N. Milligan.
11. Microsoft SharePoint 2016 for Dummies by Rosemarie and Ken Withee.
12. Project Management Lite: Just Enough to Get the Job Done Nothing More by Juana Clark Craig.


To check out any of the following ebooks, go to the library catalog at http://texashealthlibrary.com. Type in the title in the search box and then click on the electronic link. If you have difficulties or want to access these at home, please contact library@dshs.texas.gov or call 512-776-7559.

1. Ethics in Health Administration, 3rd ed., by Eileen E. Morrison.
2. Guide to Reference in Medicine and Health by Christa Modschiedler.
3. Manual of Traumatic Brain Injury: Assessment and Management, 2nd ed.
4. Root Cause Analysis: A Step-By-Step Guide to Using the Right Tool at the Right Time by Matthew A. Barsalou.
5. The Skilled Facilitator: A Comprehensive Resource for Consultants, Facilitators, Coaches, and Trainers, 3rd ed., by Roger M. Schwarz.
6. Virtual Leadership: Learning to Lead Differently by Ghislaine Caulat.

*For More Information:  Employees may contact the Medical and Research Library at library@dshs.texas.gov, call 512-776-7559, or come by Moreton Building, Room M-652, to borrow a print book, receive password access to a journal, receive other research assistance, or to obtain full-text of the articles mentioned in this month's news. If you are not located on the main campus in Austin, simply let us know what you would like to borrow and we will mail it to you.

Fine print section: If any of the internet links do not open for you, please let us know and we will send you what you need. The MRL Library News e-mail is sent about once a month or when important library news or events occur. If you have co-workers who would like to subscribe, please e-mail library@dshs.texas.gov. If for any reason you would like to unsubscribe, please send an e-mail to library@dshs.texas.gov with Unsubscribe in the subject line. Recent issues of this newsletter are on the web at http://www.dshs.texas.gov/library/news.shtm. Thank you!

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Last updated October 3, 2017