The Department of State Health Services (DSHS) border area is defined as the area within 100 kilometers (or 62 miles) of the Rio Grande in the La Paz Agreement of 1986, which includes the 32 Texas Border Counties (listed below), and Mexico.
| 32 TEXAS BORDER COUNTIES |
| Brewster |
La Salle |
| Brooks |
Maverick |
| Cameron |
McMullen |
| Crockett |
Pecos |
| Culberson |
Presidio |
| Dimmit |
Real |
| Duval |
Reeves |
| Edwards |
Starr |
| El Paso |
Sutton |
| Frio |
Terrell |
| Hidalgo |
Uvalde |
| Hudspeth |
Val Verde |
| Jeff Davis |
Webb |
| Jim Hogg |
Willacy |
| Kenedy |
Zapata |
| Kinney |
Zavala |