ARLN MICRO Submission Criteria

1. Submission Criteria

Isolates that meet the criteria identified in the table below should be submitted to DSHS for further testing.

	CRPA	CRE	CRAB
Recommended Isolates(s)	P. aeruginosa that are resistant to at least one imipenem, meropenem, or doripenem AND Nonsusceptible (intermediate or resistant) to cefepime or ceftazidime	Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae and Enterobacter spp. that are resistant to any imipenem, meropenem, doripenem, or ertapenem. Providenicia, Proteus, Morganella, Citrobacter and Serratia that are resistant to any meropenem, doripenem, or ertapenem.	Acinetobacter baumanii that are resistant to imipenem, meropenem, or doripenem by standard susceptibility testing methods.
CLSI breakpoints (Minimum Inhibitory Concentrations)
Specimen type	Any non-inhibitory, non-selective agar plate or slant (e.g. Sheep Blood Agar, Tryptic Soy Agar, etc.), or broth
Lab testing offered	MALDI-TOF mass spectrometry Antimicrobial susceptibility testing (AST) Modified Carbapenem Inactivation Method (mCIM) Note: For CRE and CRPA only. Real-time polymerase chain reaction (PCR)