Other Immunization Information

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Cost-Benefit Analysis of Commonly Used Vaccines

Benefit-Cost Analysis of Commonly Used Vaccines (Savings Per Dollar Invested*)
VACCINE	DIRECT MEDICAL SAVINGS	DIRECT + INDIRECT * SAVINGS
DTaP	$ 9.00	$27.00
MMR (includes 2nd dose)	$14.20	$26.00
IPV	$ 3.03	$ 5.45
H. INFLUENZAE TYPE b	$ 3.40	$ 5.40
HEPATITIS B PERINATAL INFANT ADOLESCENT	$1.40 $0.90 $0.50	$14.70 $5.10 $3.80
VARICELLA	$ 0.90	$ 5.40

^* Indirect savings include workloss, disability, and death

SOURCE: National Immunization Program, Centers for Disease Control and Prevention, October 2003

Required Record Keeping for Vaccinations

Listing of Required Record Keeping for Vaccinations
Record	Legislation
Name and, if appropriate title of the health care provider who administers the vaccine Address where vaccine given (in the case of outreach clinics, address should be the clinic site where the record will reside) Date of vaccination Manufacturer and lot number of vaccine	1986 National Childhood Vaccine Injury Act (NCVIA) 42 U.S.C. § 300aa-25
Edition (date of publication) of Centers for Disease Control and Prevention (CDC) Vaccine Information Statement (VIS)^* provided and date provided.	1994 amendment to 42 U.S.C. Sec. 2125. § 300aa-25
Site and route of administration	Not required, but recommended. Information requested for reports to Vaccine Adverse Event Report System (VAERS).

Licensure Dates for Vaccines and Toxoids, United States

Listing of Licensure Dates for Vaccines and Toxoids, United States
VACCINE/TOXOID	DATE
Bacillus Clamette-Guerin Vaccine	1921
Diphtheria Toxoid	1926
Tetanus Toxoid	1933
Tetanus and Diphtheria Combined Toxoid	1934
Influenza Vaccine	1945
Pertussis Vaccine	1949
Tetanus, Diphtheria Toxoid and Pertussis Vaccine	1949
Mumps Vaccine, inactivated	1950
Inactivated Poliomyelitis Vaccine (Salk)	1955
Oral Poliomyelitis Vaccine (Sabin)	1961
Trivalent Oral Polio Vaccine	1963
Measles Vaccine, live	1963
Measles Vaccine, inactivated	1963
Mumps Vaccine, live	1967
Rubella Vaccine, live	1969
Measles-Rubella Combined Vaccine, live	1971
Measles-Mumps-Rubella Vaccine, live	1971
Pneumococcal Vaccine (14-valent)	1977
Human Diploid Cell Vaccine (Rabies Vaccine)	6/80
Hepatitis B Vaccine	11/81
Pneumococcal Vaccine (23-valent)	1983
Haemophilus influenzae Type b Polysaccharide Vac.	4/85
Enhanced-Inactivated Poliomyelitis Vaccine	11/85
Hepatitis B Vaccine (RECOMBIVAX HB®)	7/86
IPOL^TM Poliovax^TM	1987
Haemophilus influenzae Type b Conjugate Vaccine	12/87
Diphtheria-Tetanus-Pertussis (Acellular) Vaccine	12/17/91 (Lederle) 8/21/92 (Connaught)
Diptheria-Tetanus-Pertusis Haemophilus influenzae Type b Conjugate Combination Vaccine	3/30/93 11/93 (2nd product)
Hepatitis A Vaccine - 3 dose schedule (SmithKline Beecham)	2/95
Varicella Vaccine	3/17/95
Hepatitis A Vaccine - 2 dose schedule (Merck Vaccine Division)	3/29/96
Diphtheria-Tetanus-Pertussis (Acellular) Vaccine for infants	7/31/96 (Connaught)
Diphtheria-Tetanus-Pertussis (Acellular)/ Haemophilus influenzae Type b Conjugate Combination Vaccine (4th dose at 15 to 18 months)	9/30/96
Haemophilus influenzae type b conjugate (Meningococcal Protein Conjugate) and Hepatitis B (Recombinant Vaccine) COMVAX	10/02/96
Diptheria & Tetanus Toxoids Adsorbed (Chiron Behring GmbH - with SKB)	1/29/97
Diphtheria-Tetanus-Acellular Pertussis (Infanrix) (Chiron Behring GmbH-with SKB)	1/29/97
Diphtheria & Tetanus Toxoids Adsorbed (Connaught Labs. Ltd) (Children, 6 weeks to 7 years of age).	4/11/97
Rabies Vaccine (Chiron Behring GmbH-Germany)	10/97
Rotavirus Vaccine (Wyeth-Lederle: RotaShield)	8/31/98
Hepatitis B Vaccine - Merck - 5.0 mcg for ages 0-19 years old	8/98
Lyme Vaccine (SmithKline Beecham Biologicals: LYMErix)	12/21/98
Pneumococcal Conjugate Vaccine (Wyeth-Lederle: Prevnar^TM)	2/17/2000

SOURCE: U.S. Department of Health and Human Services, Public Health Service, Food and Drug Administration
Texas Department of State Health Services, Immunization Branch (as of February 22, 2000).