• DSHS TB and Hansen's Disease Branch
    Post Office Box 149347, MC 1873
    Austin, Texas 78714

    Phone: 737-255-4300
    Fax: 512-989-4010

    Email the TB Program

    Email data requests to the TB Program

About Tuberculosis


Sneeze

Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis, a germ that is spread from person to person through the air. TB usually affects the lungs, but it can also affect other parts of the body, such as the brain, the kidneys or the spine. A person with TB disease can die if they do not get treatment.

TB germs are put into the air when a person with TB disease of the lungs or throat coughs, sneezes, speaks or sings. These germs can stay in the air for several hours, depending on the environment. People who breathe in the air containing these TB germs can become infected; this is called TB infection (also known as latent TB infection). If untreated, TB infection can become TB disease.


The Difference Between TB Infection and TB Disease

People with TB infection have TB germs in their bodies, but they are not sick because the germs are not active. These people do not have symptoms of TB disease and they cannot spread the germs to others. However, they may develop TB disease in the future. They are often prescribed treatment to prevent them from developing TB disease.


Symptoms of TB Disease

People with TB disease may have symptoms such as a cough, fever, chills, night sweats, weight loss, or feeling tired and unwell. They can spread the germs to others. They must take treatment for the disease to get better so they cannot spread TB to other people.

TB Infection TB Disease
  • Positive TB skin or blood test
  • No symptoms; not sick
  • Cannot spread the germs to others
  • May take treatment to prevent TB disease
  • May have a positive or negative TB skin or blood test
  • May have symptoms such as a cough, fever, night sweats, losing weight
  • Can spread the germs to others
  • Needs treatment to cure the disease


Tuberculosis Screening

There are two ways to screen for tuberculosis infection:

  • The Tuberculin Skin Test (TST)
  • Blood tests known as Interferon Gamma Release Assays (IGRAs)

Differences between TST and IGRA tests for TB infection

TST IGRA
Single patient visit No, 2 visits, one to place the test & one to read test, 2-3 days later. Yes, the test is collected on a single blood draw
Test results Subjective, because someone must place and read the test correctly Objective, because the test is processed in a laboratory after the blood draw.
Results affected by Bacillus Calmette-Guerin (BCG) Vaccine Yes, this test can show a false positive reaction to BCG No, this test does not interact with the BCG vaccination status


Tuberculosis Treatment

Treating TB disease generally requires many medications given for six to nine months. Treating people with drug-resistant TB requires different medications and patients may be on these medications for up to a year or even two years.

TB infection can be treated using shorter course medication regimens for a shorter amount of time. You must take all the medicine prescribed so that the infection is cured.


Directly Observed Therapy

TB clinics treat TB disease through what is called directly observed therapy (DOT). DOT involves a health care worker (HCW) meeting with the patient on the days when medication is prescribed, so that the HCW watches the patient take their medication. This helps to make sure the person is cured of TB and allows the TB nurse or HCW to closely monitor the person for medication side effects. DOT is required for every person in Texas with known or suspected active TB disease and recommended for children under age five with known or suspected TB infection.

Visit Frequently Asked Questions for more answers.

Lung with TB

Signs and Symptoms of Active TB

Take on TB
Take on TB in Texas (PDF)

TB Provider Fact Sheet
1 2 3s of TB (PDF)

Learn more



Last updated May 25, 2021